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Vastu Vihar Biotech: Developing Reliable Therapeutic Solutions For Autoimmune Diseases

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Vinay Tiwary, Director,Satyam Tiwari, CEO

Vinay Tiwary, Director

Satyam Tiwari, CEO

Autoimmune diseases today account for around 4 percent of the world population and are also considered the third most common cause of chronic illness in countries such as the United States. These are generally life long and are a result of an overactive immune system that mistakenly starts killing the healthy cells, ultimately leading to several other complexities of the body.

Most patients suffer from chronic conditions of the liver, kidney or skin, etc. and majority of them have autoimmune conditions that occur due to the chemokine and cytokine storm in the body. Also, the recent pandemic has been an eye opener for the world in a similar way. "Most deaths during COVID-19 pandemic have been either due to multiple organ disorders or the pro inflammatory response/various autoimmune conditions of the body. That was when we realized, our drug molecule, which is an exRNA, having an anti inflammatory and immune suppressant competence is an answer to all the challenges that we have been facing to date," says Mr. Vinay Tiwary, Director, Vastu Vihar Biotech.

"Vastu vihar vision is to become one of the leading contributors by devoting all their time and resources in finding ways to help control diseases which have been challenging the existence of mankind"

Committed to finding a possible cure
Vastu Vihar Biotech is an emerging drug development company committed to finding a possible cure for certain autoimmune diseases. The company focuses on specific techniques that include Extracellular RNA based therapies which can help in accelerating the discovery of a novel therapeutic solution for the benefit of patients as well as healthcare providers.

"We at Vastu Vihar Biotech are committed to finding a novel drug therapy using exRNA as its drug molecule, which is unlike the currently available drugs in the market, capable of providing long lasting, reliable, non-toxic, and also a cost effective therapeutic solution for the globally prevalent, non-curable, and complex autoimmune diseases such as Psoriasis, Rheumatoid Arthritis, Multiple Sclerosis, Asthma, Chronic Obstructive Pulmonary Disorder(COPD), Polycystic Ovary Syndrome (PCOS)etc.,"explains Mr. Vinay Tiwary.

Accelerating the discovery of novel therapeutic solutions
Vastu Vihar Biotech focuses on ribozyme technology to accelerate the discovery of novel therapeutic solutions for the benefit of patients and healthcare providers. However, therapeutic development and its regulatory procedures are expensive as well as time consuming. Therefore, it needs the patience of investors and academics as well.

Accelerating the discovery of novel therapeutic solutions
Vastu Vihar Biotech focuses on ribozyme technology to accelerate the discovery of novel therapeutic solutions for the benefit of patients and healthcare providers. However, therapeutic development and its regulatory procedures are expensive as well as time consuming. There fore, it needs the patience of investors and academics as well.

Finding a novel therapeutic solution
"In 100 years of drug development, new chemical entities and small peptide molecules have worked miraculously. However, most diseases remain clueless due to lack of adequate research. There is no possible cure for various autoimmune diseases that are becoming a major concern worldwide," says Mr. Satyam Tiwari, CEO, Vastu Vihar Biotech.

“We at Vastu Vihar Biotech, with a commitment to finding a novel therapeutic solution for addressing such challenges, are working upon RNA as our drug molecule with an achieved success in both fields such as autoimmune diseases and cancer,"he adds.

Developing a drug molecule with immune suppressant competence
Incepted in 2014, Vastu Vihar Biotech Private Limited has stayed focused on finding a reliable and long lasting therapeutic solution for serious diseases where it could achieve a prodigious impact for patients, not just an incremental benefit. In addition to it, Vastu
Vihar Biotech has DSIR approved biotech lab. Vastu Vihar Biotech is a part of VastuVihar Group which is functional in a different arena.

Realizing, the available drug therapies are short term and fail to target the root cause of the disease, the company has been focusing on the mechanism in which, targeting and down regulation of responsible genes, cytokines, and chemokines or the pathways involved in the development of the disease is prioritized. Vastu Vihar Biotech, unlike the existing solutions, does not aim to provide temporary solutions, rather it is working towards the development of a drug molecule, namely exRP250, which is an exRNA having an anti inflammatory as well as immune suppressant competence.

In 100 years of drug development, new chemical entities and small peptide molecules have worked miraculously


Robust team
The Vastu Vihar team comprises various group of experts who have pursued PhDs and Masters in the biotechnology field. Not just that, but the team also consists of students pursuing their Masters' degrees, working with VastuVihar on technologies. The company is currently working with different laboratories across India and different countries around the world for characterization of the drug molecule, animal studies of the molecule on different disease models that include other autoimmune diseases such as psoriasis, asthma etc.

VastuVihar team also has 25 scientists who are working on the diagnostics projects and 55 Scientists from molecular biology cell culture, micro biology, micro fluidics, mechanical, electrical, electronics, computer science departments.

"Our vision is to become one of the leading contributors to the service of mankind. We are devoting all our time and resources in finding ways to help control some of the deadly diseases which have been challenging the existence of mankind,"affirms Mr. Satyam Tiwary.


The road ahead
"Since we are in the startup phase we are focused more on strengthening our research pathway and achieving our discovery targets rather than hurrying ourselves to augment the marketing process and selling our drug. Currently, we are undergoing the crucial regulatory phase and we are soon planning to initiate the IND (Investigational new drug) procedures for the treatment of Psoriasis, which is a persistent as well as relapsing inflammatory skin disease that usually occurs due to the autoimmune hyper response and strong genetic predisposition," says Mr. Vinay Tiwary.

"Also, our upcoming drug `VV Psoriasis Spray' is a proprietary medicine that has been approved by the `Ministry of Ayush' under the category of Ayurvedic medicine for the treatment of Psoriasis," he concludes.

Striving to create a disease free nation
While Vastu Vihar is steadfastly investing in developing novel therapies for certain life threatening diseases, the company is committed to making its medicines easily accessible to patients all over the world, at affordable prices. We strive to create a disease-free nation. "Being a Research & Development unit, it is our duty to provide reliable, 100 percent efficient, and long lasting healthcare solutions for a healthy future," says Vinay. Vastu Vihar Biotech has also made its priority to be able to come up with a cost efficient drug therapy that can prove to be beneficial for all.

Approaching towards the pre clinical and clinical trials for Vastu Vihar's potential drug based on Ribozyme concerning various auto immune diseases, the company exhibits a strong will to conquer millions of hearts as well as emerge victorious in every aspect of its business. With its team of well qualified and passionate researchers, the company is working towards finding possible ways to contribute to a healthy and disease free nation.

Well Equipped Laboratories
Vastu Vihar has ISO-9001:2015 certified analytical laboratories and more than 25 acre areas covering labs and offices. It has 12 well equipped laboratories such as microbiology lab, molecular biology lab, cell culture lab, and tissue culture lab. These are certified by the Department of Scientific & Industrial Research. The company also comprises an inhouse R&D center and considers its teams as an important asset contributing to the growth of the company.

The microbiology lab of Vastu Vihar is located within the campus. The lab is well equipped with all the possible facilities needed for executing research work smoothly. Apart from the microbiology lab, the company also has a well equipped Molecular biology lab, cell culture lab, and Bio instrumentation lab, where in protocols are followed. All labs of VastuVihar are BSL-2 approved and licensed by the Department of Scientific and Industrial Research(DSIR).